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1

The Mu-Opioid Receptor Agonist/Noradrenaline Reuptake Inhibition (MOR–NRI) Concept in Analgesia: The Case of Tapentadol

Tzschentke, Thomas M., Christoph, Thomas, Kögel, Babette Y.

Journal:

Year:

2014

Language:

english

File:

PDF, 553 KB

english, 2014

2

The influence of wind speed on heat production in laying hybrids (Gallus domesticus) of different ages at various relative humidities

B. Tzschentke, M. Nichelmann

Journal:

Journal of Thermal Biology

Year:

1986

Language:

english

File:

PDF, 384 KB

english, 1986

3

The medial prefrontal cortex as a part of the brain reward system

T. M. Tzschentke

Journal:

Year:

2000

Language:

english

File:

PDF, 77 KB

english, 2000

4

Influence of feather cover on heat balance in laying hens (Gallus domesticus)

M. Nichelmann, E. Baranyiová, R. Goll, B. Tzschentke

Journal:

Journal of Thermal Biology

Year:

1986

Language:

english

File:

PDF, 401 KB

english, 1986

5

Synergistic Interaction between the Two Mechanisms of Action of Tapentadol in Analgesia

Schroder, W., Tzschentke, T. M., Terlinden, R., De Vry, J., Jahnel, U., Christoph, T., Tallarida, R. J.

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2011

Language:

english

File:

PDF, 1.12 MB

english, 2011

6

RNA interference-mediated silencing of Kv7.2 in rat dorsal root ganglion neurons abolishes the anti-nociceptive effect of a selective channel opener

Valdor, Markus, Wagner, Anke, Fischer, Heike, RÃ¶hrs, Viola, SchrÃ¶der, Wolfgang, Bahrenberg, Gregor, Welbers, AndrÃ©, Fechner, Henry, Kurreck, Jens, Tzschentke, Thomas M., Christoph, Thomas

Journal:

Journal of Pharmacological and Toxicological Methods

Year:

2020

File:

PDF, 2.77 MB

2020

7

Cebranopadol: A Novel Potent Analgesic Nociceptin/Orphanin FQ Peptide and Opioid Receptor Agonist

Linz, K., Christoph, T., Tzschentke, T. M., Koch, T., Schiene, K., Gautrois, M., Schroder, W., Kogel, B. Y., Beier, H., Englberger, W., Schunk, S., De Vry, J., Jahnel, U., Frosch, S.

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2014

Language:

english

File:

PDF, 1.41 MB

english, 2014

8

Mu-opioid peptide (MOP) and nociceptin/orphanin FQ peptide (NOP) receptor activation both contribute to the discriminative stimulus properties of cebranopadol in the rat

Tzschentke, Thomas M., Rutten, Kris

Journal:

Neuropharmacology

Year:

2018

Language:

english

File:

PDF, 1.14 MB

english, 2018

9

Effect of acclimation temperature on the heat balance of adult rabbits (Oryctolagus cuniculus)

B. Tzschentke, M. Nichelmann, T. Paetzel, H. Dulder, T. Postel

Journal:

Journal of Thermal Biology

Year:

1990

Language:

english

File:

PDF, 516 KB

english, 1990

10

Ahead of their time? Barriers to action in green tourism firms

Tzschentke, Nadia, Kirk, David, Lynch, Paul

Journal:

Service Industries Journal

Year:

2008

Language:

english

File:

PDF, 119 KB

english, 2008

11

F140 PHARMACOLOGICAL AND METABOLIC DIFFERENTIATION OF THE ANALGESICS TAPENTADOL AND TRAMADOL

T.M. Tzschentke, B.Y. Kögel, W. Schröder, J. De Vry, K. Schiene, W. Englberger, R. Terlinden, T. Christoph

Journal:

European Journal of Pain Supplements

Year:

2011

Language:

english

File:

PDF, 57 KB

english, 2011

12

Influence of Temperature Manipulation during the Last 4 Days of Incubation on Hatching Results, Post-Hatching Performance and Adaptability to Warm Growing Conditions in Broiler Chickens

Halle, Ingrid, Tzschentke, Barbara

Journal:

The Journal of Poultry Science

Year:

2011

File:

PDF, 323 KB

2011

13

Metabolic responses of chicken and muscovy duck embryos to high incubation temperatures

Oliver Janke, Barbara Tzschentke, Joachim Höchel, Martin Nichelmann

Journal:

Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology

Year:

2002

Language:

english

File:

PDF, 190 KB

english, 2002

14

Prenatal Development of Epigenetic Adaptation Processes in Poultry: Changes in Metabolic and Neuronal Thermoregulatory Mechanisms

Loh, B., Maier, I., Winar, A., Janke, O., Tzschentke, B.

Journal:

Avian and Poultry Biology Reviews

Year:

2004

Language:

english

File:

PDF, 254 KB

english, 2004

15

Monitoring the development of thermoregulation in poultry embryos and its influence by incubation temperature

Journal:

Computers and Electronics in Agriculture

Year:

2008

Language:

english

File:

PDF, 1.22 MB

english, 2008

16

Going green: Decisional factors in small hospitality operations

Nadia A. Tzschentke, David Kirk, Paul A. Lynch

Journal:

International Journal of Hospitality Management

Year:

2008

Language:

english

File:

PDF, 190 KB

english, 2008

17

Effects of ambient temperature, age and wind speed on the thermal balance of layer‐strain fowls

Tzschentke, B., Nichelmann, M., Postel, T.

Journal:

British Poultry Science

Year:

1996

Language:

english

File:

PDF, 1.01 MB

english, 1996

18

Effects of the NOP receptor agonist Ro65-6570 on the acquisition of opiate- and psychostimulant-induced conditioned place preference in rats

Kris Rutten, Jean De Vry, Walter Bruckmann, Thomas M. Tzschentke

Journal:

European Journal of Pharmacology

Year:

2010

Language:

english

File:

PDF, 1.22 MB

english, 2010

19

Lesions of the medial preoptic area/anterior hypothalamus (MPOA/AH) modify partner preference in male rats

Raúl G Paredes, Tanya Tzschentke, Nancy Nakach

Journal:

Year:

1998

Language:

english

File:

PDF, 271 KB

english, 1998

20

Mechanical hyperalgesia in rats with diabetic polyneuropathy is selectively inhibited by local peripheral nociceptin/orphanin FQ receptor and µ-opioid receptor agonism

Schiene, Klaus, Tzschentke, Thomas M., Schröder, Wolfgang, Christoph, Thomas

Journal:

European Journal of Pharmacology

Year:

2015

Language:

english

File:

PDF, 808 KB

english, 2015

21

DNA methylation and expression of proopiomelanocortin ( POMC ) gene in the hypothalamus of three-week-old chickens show sex-specific differences

Rancourt, Rebecca C., Schellong, Karen, Tzschentke, Barbara, Henrich, Wolfgang, Plagemann, Andreas

Journal:

Year:

2018

Language:

english

File:

PDF, 470 KB

english, 2018

22

Reassessment of buprenorphine in conditioned place preference: temporal and pharmacological considerations

ThomasM. Tzschentke

Journal:

Psychopharmacology

Year:

2004

Language:

english

File:

PDF, 335 KB

english, 2004

23

S107 SPINAL OPIOIDERGIC AND NORADRENERGIC MECHANISMS CONTRIBUTE TO THE ANTIHYPERALGESIC EFFECT OF TAPENTADOL IN DIABETIC NEUROPATHIC MICE

T. Christoph, J. De Vry, W. Schröder, T.M. Tzschentke

Journal:

European Journal of Pain Supplements

Year:

2011

Language:

english

File:

PDF, 55 KB

english, 2011

24

Spinal-Supraspinal and Intrinsic -Opioid Receptor Agonist-Norepinephrine Reuptake Inhibitor (MOR-NRI) Synergy of Tapentadol in Diabetic Heat Hyperalgesia in Mice

Christoph, T., Schroder, W., Tallarida, R. J., De Vry, J., Tzschentke, T. M.

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2013

Language:

english

File:

PDF, 392 KB

english, 2013

25

Procedural examination of behavioural sensitisation to morphine

Tzschentke, T. M., Schmidt, W. J.

Journal:

Behavioural Pharmacology

Year:

1996

File:

PDF, 1.33 MB

1996

26

State-dependent blockade of haloperidol-induced sensitization of catalepsy by MK-801

Werner J. Schmidt, Thomas M. Tzschentke, Beate D. Kretschmer

Journal:

European Journal of Neuroscience

Year:

1999

Language:

english

File:

PDF, 187 KB

english, 1999

27

The mGluR5 antagonist 2-methyl-6-(phenylethynyl)-pyridine (MPEP) potentiates conditioned place preference induced by various addictive and non-addictive drugs in rats

Kris Rutten, Elizabeth L. Van Der Kam, Jean De Vry, Walter Bruckmann, Thomas M. Tzschentke

Journal:

Addiction Biology

Year:

2011

Language:

english

File:

PDF, 573 KB

english, 2011

28

Pharmacology and behavioral pharmacology of the mesocortical dopamine system

T.M. Tzschentke

Journal:

Progress in Neurobiology

Year:

2001

Language:

english

File:

PDF, 506 KB

english, 2001

29

S182 CRITICAL APPRAISAL OF THE CONDITIONED PLACE PREFERENCE PARADIGM AS READOUT FOR SPONTANEOUS PAIN IN STREPTOZOTOCIN-INDUCED DIABETIC RATS

K. Rutten, T.M. Tzschentke, T. Christoph, J. De Vry, W. Schröder

Journal:

European Journal of Pain Supplements

Year:

2011

Language:

english

File:

PDF, 55 KB

english, 2011

30

The nociceptin/orphaninFQ receptor system as a target to alleviate cancer‐induced bone pain in rats: Model validation and pharmacological evaluation

Sliepen, Sonny H.J., Korioth, Johanna, Christoph, Thomas, Tzschentke, Thomas M., Diaz‐delCastillo, Marta, Heegaard, Anne‐Marie, Rutten, Kris

Journal:

British Journal of Pharmacology

Year:

2019

Language:

english

File:

PDF, 1.59 MB

english, 2019

31

The serotonin/noradrenaline reuptake inhibitor venlafaxine attenuates acquisition, but not maintenance, of intravenous self-administration of heroin in rats

Zofia Magalas, Jean De Vry, Thomas M. Tzschentke

Journal:

European Journal of Pharmacology

Year:

2005

Language:

english

File:

PDF, 158 KB

english, 2005

32

Tzschentke and Schmidt reply

Thomas M Tzschentke, Werner J Schmidt

Journal:

Trends in Pharmacological Sciences

Year:

1999

Language:

english

File:

PDF, 87 KB

english, 1999

33

Measuring reward with the conditioned place preference paradigm: a comprehensive review of drug effects, recent progress and new issues

Thomas M. Tzschentke

Journal:

Progress in Neurobiology

Year:

1998

Language:

english

File:

PDF, 907 KB

english, 1998

34

The nociceptin/orphaninFQ receptor system as a target to alleviate cancer‐induced bone pain in rats: Model validation and pharmacological evaluation

Sliepen, Sonny H.J., Korioth, Johanna, Christoph, Thomas, Tzschentke, Thomas M., Diaz‐delCastillo, Marta, Heegaard, Anne‐Marie, Rutten, Kris

Journal:

British Journal of Pharmacology

Year:

2019

File:

PDF, 1.59 MB

2019

35

Influence of bombesin on neuronal hypothalamic thermosensitivity during the early postnatal period in the Muscovy duck (Cairina moschata)

Barbara Tzschentke, Dietmar Basta, Alexander V Gourine, Valerie N Gourine

Journal:

Regulatory Peptides

Year:

2000

Language:

english

File:

PDF, 237 KB

english, 2000

36

The Noradrenergic Component in Tapentadol Action Counteracts -Opioid Receptor-Mediated Adverse Effects on Adult Neurogenesis

Meneghini, V., Cuccurazzu, B., Bortolotto, V., Ramazzotti, V., Ubezio, F., Tzschentke, T. M., Canonico, P. L., Grilli, M.

Journal:

Molecular Pharmacology

Year:

2014

Language:

english

File:

PDF, 1.46 MB

english, 2014

37

Influence of temperature stimulation during the last 4 days of incubation on secondary sex ratio and later performance in male and female broiler chicks

Tzschentke, B., Halle, I.

Journal:

British Poultry Science

Year:

2010

Language:

english

File:

PDF, 42 KB

english, 2010

38

Selectivity profiling of NOP, MOP, DOP and KOP receptor antagonists in the rat spinal nerve ligation model of mononeuropathic pain

Rutten, Kris, Schröder, Wolfgang, Christoph, Thomas, Koch, Thomas, Tzschentke, Thomas M.

Journal:

European Journal of Pharmacology

Year:

2018

Language:

english

File:

PDF, 747 KB

english, 2018

39

711 ANTI-ALLODYNIC ACTIVITY OF TAPENTADOL IN A RAT MODEL OF NEUROPATHIC PAIN DEPENDS ON OPIOID AND NORADRENERGIC, BUT NOT SEROTONERGIC, MECHANISMS

T. Christoph, J. De Vry, U. Jahnel, T.M. Tzschentke

Journal:

European Journal of Pain

Year:

2009

Language:

english

File:

PDF, 46 KB

english, 2009

40

Effect of GABAergic substances on firing rate and thermal coefficient of hypothalamic neurons in the juvenile chicken

Nagaraja Sallagundala, Krassimira Yakimova, Barbara Tzschentke

Journal:

Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology

Year:

2007

Language:

english

File:

PDF, 710 KB

english, 2007

41

N-Methyl-d-aspartic acid-receptor antagonists block morphine-induced conditioned place preference in rats

Thomas M. Tzschentke, Werner J. Schmidt

Journal:

Neuroscience Letters

Year:

1995

Language:

english

File:

PDF, 464 KB

english, 1995

42

Differential effects of morphine on the affective and the sensory component of carrageenan-induced nociception in the rat

Elizabeth Louise van der Kam, Jean De Vry, Klaus Schiene, Thomas Michael Tzschentke

Journal:

Year:

2008

Language:

english

File:

PDF, 209 KB

english, 2008

43

Imprinting and critical periods in early development

TZSCHENTKE, B., PLAGEMANN, A.

Journal:

World's Poultry Science Journal

Year:

2006

Language:

english

File:

PDF, 249 KB

english, 2006

44

Early-age cold conditioning of broilers: effects of timing and temperature

Shahir, M.H., Dilmagani, S., Tzschentke, B.

Journal:

British Poultry Science

Year:

2012

Language:

english

File:

PDF, 77 KB

english, 2012

45

CYTOKINE-INDUCED PLASTICITY OF HYPOTHALAMIC CRH-NEURONS AND SENSITIZATION TO STRESS

TZSCHENTKE, T M, SCHMIDT, W J

Journal:

Behavioural Pharmacology

Year:

1996

File:

PDF, 213 KB

1996

46

Behavioral pharmacology of buprenorphine, with a focus on preclinical models of reward and addiction

Thomas M. Tzschentke

Journal:

Psychopharmacology

Year:

2002

Language:

english

File:

PDF, 103 KB

english, 2002

47

196 TAPENTADOL, A NOVEL CENTRALLY ACTING ANALGESIC: PRECLINICAL EVIDENCE FOR A DUAL MODE OF ACTION UNDERLYING ITS BROAD EFFICACY PROFILE

T.M. Tzschentke, J. De Vry, T. Christoph, B. Kögel, K. Schiene, H.H. Hennies, W. Englberger, U. Jahnel, T.I.F.H. Cremers, E. Friderichs

Journal:

European Journal of Pain

Year:

2006

Language:

english

File:

PDF, 49 KB

english, 2006

48

Tramadol increases extracellular levels of serotonin and noradrenaline as measured by in vivo microdialysis in the ventral hippocampus of freely-moving rats

P. Bloms-Funke, E. Dremencov, T.I.F.H. Cremers, T.M. Tzschentke

Journal:

Neuroscience Letters

Year:

2011

Language:

english

File:

PDF, 216 KB

english, 2011

49

Tapentadol: mit zwei Mechanismen in einem Molekül wirksam gegen nozizeptive und neuropathische Schmerzen

T.M. Tzschentke, T. Christoph, W. Schröder, W. Englberger, J. De Vry, U. Jahnel, B.Y. Kögel

Journal:

Year:

2011

Language:

german

File:

PDF, 497 KB

german, 2011

50

317 ANTI-NOCICEPTIVE ACTIVITY OF TAPENTADOL IN A RAT MODEL OF ACUTE PAIN DEPENDS ON OPIOID AND NORADRENERGIC, BUT NOT SEROTONERGIC, MECHANISMS

W. Schröder, J. De Vry, T.M. Tzschentke

Journal:

European Journal of Pain

Year:

2009

Language:

english

File:

PDF, 46 KB

english, 2009

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